|
Table1. Cytotoxicity
of Eleutherococcus
senticosus extracts
against
human cancer cell lines
Naturally Cultivated (root extracts) (GI50 : ㎍/㎖)
materials |
Prostate
(PC-3) |
Colon
(HCT-15) |
Renal
(ACHN) |
Colon
(SW-620) |
Lung
(A549) |
Leukemia
(MOLT-4F) |
GI50 |
MeOH extract |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Hexane layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
EtOAc layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
n-BuOH layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Aqueous layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Adriamycin |
0.33 |
0.32 |
0.48 |
0.17 |
0.41 |
0.24 |
0.33 |
Cell-Cultured Plantlets (GI50 : ㎍/㎖)
materials |
Prostate
(PC-3) |
Colon
(HCT-15) |
Renal
(ACHN) |
Colon
(SW-620) |
Lung
(A549) |
Leukemia
(MOLT-4F) |
GI50 |
MeOH extract |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Hexane layer |
22.9 |
>
30 |
18.21 |
21.99 |
>
30 |
13.57 |
22.78 |
EtOAc layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
n-BuOH layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Aqueous layer |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
>
30 |
Adriamycin |
0.13 |
0.16 |
0.13 |
0.03 |
0.03 |
0.05 |
0.09 |
Table 2. Scavenging effect of
Eleutherococcus
senticosus extracts
against
DPPH freeradicals
Naturally Cultivated (root extracts)
materials |
RC50(㎍/㎖) |
MeOH extract |
20 |
Hexane layer |
>
100 |
EtOAc layer |
10 |
n-BuOH layer |
16
|
Aqueous layer |
38 |
α-Tocopherol |
12 |
Cell-Cultured Plantlets
materials |
RC50(㎍/㎖) |
MeOH extract |
12 |
Hexane layer |
>
50 |
EtOAc layer |
4 |
n-BuOH layer |
6
|
Aqueous layer |
19 |
α-Tocopherol |
12 |
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